White Hart Lane is the venue on Sunday afternoon as Spurs host Man Utd in what should be a cracker.
Tottenham boss Andre Villas-Boas will recall several first-team regulars, having made nine changes for Thursday's win in Tromso.
Forward Emmanuel Adebayor is a doubt because of a groin injury, while Christian Eriksen, Danny Rose and Harry Kane all remain unavailable
Manchester United pair Robin van Persie and Nemanja Vidic could return after respective groin and head injuries.
Spurs are winless in their last 12 games in this fixture at White Hart Lane, and their poor league form of late does little to suggest they can change that record on Sunday, especially after the humiliation of being battered 6-0 by Man City last weekend.
United’s confidence will no doubt be high after thumping German outfit Bayer Leverkusen on Wednesday and the superb form of Wayne Rooney is a boost to manager David Moyes, who will need him to perform in such a tough game.
This game will sure to be a tight one, with only one of Spurs’ home league matches this season providing over two goals.
Tottenham v Manchester United Betting Tips
Draw 1-1 @ 6/1 – Bet Victor
Wayne Rooney to score anytime @ 12/5 – Bet 365
Under 2.5 Goals @ 20/23 – Bet Victor